Description

Pentorse 100 Injection contains Pentosan Polysulfate Sodium. It aids in the treatment of non-infectious inflammatory joint diseases in dogs. Pentosan Polysulphate is derived from a plant source called beechwood.

Composition:

Each ml contains

Pentosan Polysulfate Sodium 100 mg

Indications

Osteo-arthritis & Traumatic joint disease
Osteo-chondrosis dessicans
Degenerative cartilaginous joint disease
Musculoskeletal Disorder.
Peri-articular Inflammation

Benefits

Completely safe and no reported side effects
Anti-inflammatory Action helps reducing joint inflammation and pain.
Fibrinolytic Activity
Chondroprotective action and inhibition of loss of proteoglycans helps in terminating further destruction of the joint and initiates regeneration of the damaged tissue.
Stimulation of Hyaluronic Acid increases formation of synovial fluid which helps in lubrication of the joint.
Inhibition of Destructive Enzymes
Reverses effects of Osteoarthritis
Technically the product shows a long-term effect as compared to other treatment options

Contradictions

Pentosan being a plant-based origin it doesn’t have any side effects in the body but occasionally if a patient is hypersensitive they may show gastric sensitivity like Emesis, diarrhoea, lethargy and anorexia.
We also need to take precautions in the following cases:
Do not use for the treatment of septic arthritis. In this case, appropriate antimicrobial therapy should be instigated.
Do not use in dogs with advanced liver or kidney impairment, or evidence of infection.
Do not use in dogs with blood disorders, coagulation disorders, bleeding or malignancy (especially haemangiosarcoma).
Pentosan Polysulfate has an anticoagulant effect. Do not use during the pre-operative period.
Do not use in the skeletally immature dog (i.e. dogs whose long bone growth plates have not closed).
Do not administer in Pregnant or lactating bitches.
NSAID and In particular Aspirin should not be used in combination with pentosan as they may affect thrombocyte adhesion and potentiate anticoagulant activity of the product.
Corticosteroid have been shown to be antagonist to a number of action of pentosan.

Dosage of Pentorse 100

Should be strictly used under the guidance of a veterinarian

The dosage for canine is 3mg/kg BW (1 ml per 33 kg BW) given subcutaneously every 5-7 days for a period of 4 weeks.
Can be repeated after one month’s rest period.
Not more than 3 courses a year i.e. 12 injections in a year.
Category: Pharmaceuticals

Additional information

Brand	Vetina
Size	2 ML